Description
Product Characteristics: Target Information: Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity). Involved in regulation of cell intracellular organization (PubMed:26386247). Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415). {ECO:0000250:UniProtKB:Q1G7G9, ECO:0000269:PubMed:21750036, ECO:0000269:PubMed:25251415, ECO:0000269:PubMed:26386247}